Glucosamine also known as 2-amino-2-deoxy glucose is a natural amino sugar available in chitin. Chitin is a polysaccharide found in the outer skeleton of shrimps and crabs. Chitin is extracted through the process of decalcination, deprotenation etc.
Methyl Sulfonyl Methane (MSM) is a naturally occurring organic compound. Recent interest in sulphur has been stimulated by its use in the form of Methyl Sulfonyl Methane on human beings. Sulphur is important in the formation of Collagen and Glucosamine that are necessary for the maintenance of healthy bones, Joints, ligaments and tendons. A direct relationship between the amount of MSM present in the body and resistance to allergies has been established. MSM is essential for the production of keratin, collagen, and important constituents of hair, skin and nails. MSM is also useful in producing the insulin in the body, which makes cells more permeable thereby allowing them to absorb blood sugar.
Data Sheet
Name of the Product
: Glucosamine Hydrochloride USP
Chemical Name
: 2-Amino-2-deoxy-D-glucose hydrochloride
Molecular Formula
: C6H13NO5.HCl
Molecular Weight
: 215.64
CAS Number
: 66-84-2
Structure
Glucosamine also called as 2-amino-2-deoxy glucose is a natural amino sugar available in chitin. Chitin is a polysaccharide found in the outer skeleton of shrimps and crabs. Chitin is extracted through the process of decalcination, deprotenation etc.
Specification
test
specification
Appearance
White
crystalline Powder
Identification
I.R Absorption
The IR absorption spectrum of the sample should
be concordant with the reference spectrum of Glucosamine Hydrochloride WS.
Chloride Test
It meets the requirements of the tests for
chloride.
HPLC – Retention time
The Retention time of the sample assay peak
corresponds to that WS peak.
Physio - Chemical Analysis
Solubility
Freely soluble in Water.
Loss On Drying, 2 hrs at 105 Deg. C (% w/w)
NMT 1.0
Sp. Optical Rotation, 25mg/ml ( Deg).
+ 70.0 to +73.0
Residue on Ignition, (% w/w)
NMT 0.1
PH (20 mg/ml)
3.0 to 5.0
Sulfate (% w/w)
NMT 0.24
Particle Size ( % w/w)
100 % Passing through 40/60/80/100 mesh.
Arsenic (ppm)
NMT 3
Heavy metals (ppm)
NMT 10
Assay, on dried basis (% w/w)
98 - 102
Data Sheet
Name of the Product
: Glucosamine Sulphate potassium chloride USP
Chemical Name
: Bis(D-Glucose,2-amino-2-deoxy-),sulfate potassium chloride complex
Molecular Formula
: (C6H14NO5)2SO4.2KCl
Molecular Weight
: 605.52
CAS Number
: 29031-19-4
Structure
Glucosamine also
called as 2-amino-2-deoxy glucose is a natural amino sugar available in chitin.
Chitin is a polysaccharide found in the outer skeleton of shrimps and crabs.
Chitin is extracted through the process of decalcination, deprotenation etc.
Specification
test
specification
Appearance
White crystalline Powder.
Identification
I.R Absorption
The IR absorption spectrum of the sample should
be concordant with the reference spectrum of Glucosamine Hydrochloride WS.
Chloride & Potassium test
It meets the requirements of the tests for
chloride and potassium.
Reaction of sulphate.
A white precipitate is to be formed after
addition of Barium chloride TS in the test for content of sulphate.
HPLC – Retention time
The Retention time of the sample assay peak
corresponds to that WS peak.
Physio - Chemical Analysis
Solubility
Freely soluble in Water.
Loss On Drying, 2 hrs at 105 Deg. C (% w/w)
NMT 1.0
Sp. Optical Rotation, 35mg/ml. (Deg).
+ 47.0 to +53.0
Residue on Ignition ( % w/w)
26.5 – 31.0
PH, 2% Solution
3.0 to 5.0
Sulphate Content (% w/w)
15.5-16.5
Sodium
Does not impart a pronounced yellow color.
Particle size
100% passing through 40/60/80/100 mesh
Arsenic (ppm)
NMT 3.0
Heavy metals (ppm)
NMT 10
Assay, on dried basis (% w/w)
98 - 102
Data Sheet
Name of the Product
: Glucosamine Sulphate sodium chloride USP
Chemical Name
: Bis(D-Glucose,2-amino-2-deoxy-),sulfate Sodium chloride complex
Molecular Formula
: (C6H14NO5)2SO4.2NaCl
Molecular Weight
: 573.31
CAS Number
: 38899-05-7
Structure
Glucosamine also called as 2-amino-2-deoxy
glucose is a natural amino sugar available in chitin. Chitin is a polysaccharide
found in the outer skeleton of shrimps and crabs. Chitin is extracted through
the process of decalcination, deprotenation etc.
Specification
test
specification
Appearance
White crystalline Powder.
Assay, on dried basis(% W/W)
98 - 102
Identification
I.R Absorption
The IR absorption spectrum of the sample should
be concordant with the reference spectrum of Glucosamine Hydrochloride WS.
Chloride & potassium test
It meets the requirements of the tests for
chloride and Potassium.
Reaction of sulphate.
A white precipitate is to be formed after
addition of Barium chloride TS in the test for content of sulphate.
HPLC – Retention time
The Retention time of the sample assay peak
corresponds to that WS peak.
Physio - Chemical Analysis
Solubility
Freely soluble in Water.
Loss On Drying, 2 hrs at 105 Deg. C (% w/w)
NMT 1.0
Sp. Optical Rotation, 35mg/ml. (Deg).
+ 47.0 to +53.0
Residue on Ignition ( % w/w)
26.5 - 31.0
PH, 2% Solution
3.0 to 5.0
Sulphate Content (% w/w)
15.5 - 16.5
Sodium
Does not impart a pronounced yellow color.
Particle Size
100% passing through 40/60/80/100 mesh.
Arsenic (ppm)
NMT 3.0
Heavy metals (ppm)
NMT 10
Data Sheet
Name of the Product
: Methyl Sulfonyl Methane USP
Chemical Name
: Dimethyl sulfone
Molecular Formula
: C2H6O2S
Molecular Weight
: 94.13
CAS Number
: 67-71-0
Structure
Methyl Sulfonyl Methane (MSM) is a naturally
occurring organic compound. Recent interest in sulphur has been stimulated by
its use in the form of Methyl Sulfonyl Methane on human beings. Sulphur is
important in the formation of Collagen and Glucosamine that are necessary for
the maintenance of healthy bones, Joints, ligaments and tendons. A direct
relationship between the amount of MSM present in the body and resistance to
allergies has been established. MSM is essential for the production of keratin,
collagen, and important constituents of hair, skin and nails. MSM is also
useful in producing the insulin in the body which makes cells more permeable
thereby allowing them to absorb blood sugar.
Specification
test
specification
Appearance
White
Powder or flake crystal.
Identification
IR identification
The IR spectrum of the sample should be
concordant with the IR spectrum of the MSM working standard.
Retention time
The Retention time of the sample assay peak
corresponds to the Standard peak.
Physio - Chemical Analysis
Solubility
Freely Soluble in water, in methanol, in alcohol
and in acetone. Sparingly soluble in ether.
Water content (%, w/w)
NMT 0.1
Melting point ( Deg. C)
108.5 – 110.5
Particle size
100 % Passing through 40/60/80 mesh.
Heavy metals (ppm)
NMT 3
Assay (% w/w)
98 to 102
Chromatographic purity (%)
NLT 99.8
Limit of Dimethylsulfoxide as an individual impurity (%)
NMT 0.1
Any other individual impurity (%)
NMT 0.05
Total impurities (%)
NMT 0.2
Microbiological Report
Total microbial count (Cfu/g)
NMT 1000
Yeast & Mould (Cfu/g)
NMT 100
E-Col/10 g
Should be absent